CBD 101, What You Need To Know

What Is CBD Oil?

CBD is one of many compounds, known as cannabinoids, that are found in the cannabis plant. Researchers have been looking at the potential therapeutic uses of CBD. Oils that contain concentrations of CBD are known as CBD oils. The concentration and uses of different oils vary.

Is CBD Marijuana?

CBD oil is a cannabinoid derived from the cannabis plant. Until recently, the most well-known compound in cannabis was delta-9 tetrahydrocannabinol (THC). This is the most active ingredient in marijuana. Marijuana contains both THC and CBD, but the compounds have different effects. THC is well-known for the mind-altering high; it produces when broken down by heat and introduced into the body, such as when smoking the plant or cooking it into foods.

Unlike THC, CBD is not psychoactive. This means that it does not change the state of mind of the person who uses it. However, it does appear to produce significant changes in the body and has been found to have medical benefits.

Most of the CBD used medicinally is found in the least processed form of the cannabis plant, known as hemp. Hemp and marijuana come from the same plant, cannabis sativa, but they are very different. Over the years, marijuana farmers have selectively bred their plants to be very high in THC and other compounds that interested them, either for a smell or an effect they had on the plant's flowers. CBD derived from industrial hemp plant is legal in all 50 states. That’s because, just a few years ago, the U.S. federal government passed the Agricultural Act of 2014, sometimes known as the Farm Bill, which allows for the cultivation of industrial hemp in “limited” state-sponsored programs.

According to Section 7606 of the Farm Bill, industrial hemp is defined as:
“[…] the plantCannabis sativa L. and any part of such plant, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.” All of our CBD products are derived from these hemp plants that conform to the Farm Bill, having 0.3 percent THC, or more typically, no THC at all.

How CBD Works

All cannabinoids, including CBD, attach themselves to certain receptors in the body to produce their effects. The human body produces certain cannabinoids on its own. It has two receptors for cannabinoids, called CB1 receptors and CB2 receptors. CB1 receptors are found all around the body, but many of them are in the brain.

The CB1 receptors in the brain deal with coordination and movement, pain, emotions and mood, thinking, appetite, and memories, among others. THC attaches to these receptors. CB2 receptors are more common in the immune system. They affect inflammation and pain. It used to be thought that CBD acts on these CB2 receptors, but it appears now that CBD does not act on either receptor directly. Instead, it seems to influence the body to use more of its own cannabinoids.

Benefits

Because of the way that CBD acts in the body, it has many potential benefits such as natural pain relief or anti-inflammatory properties. People commonly use prescription or over-the-counter drugs to relieve pain and stiffness, including chronic pain. Some people feel that CBD offers a more natural way to lower pain. A study published in theJournal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats. The researchers suggest that the non-psychoactive compounds in marijuana, such as CBD, could be a new treatment for chronic pain.

Quitting Smoking & Narcotics Withdrawal

There is some promising evidence that CBD use may help people to quit smoking. A pilot study posted to Addictive Behaviors found that smokers who used an inhaler containing the compound CBD smoked fewer cigarettes but did not have any additional craving for nicotine. Another similar study posted to Neurotherapeutics found that CBD may be a promising substance for people who abuse opioids. Researchers noted that some symptoms experienced by patients with substance use disorders might be reduced by CBD. These include anxiety, mood symptoms, pain, and insomnia. These are early findings, but they suggest that CBD may be used to avoid or reduce withdrawal symptoms.

Epilepsy

CBD is also being studied for its possible role in treating epiliepsy. Areview posted toEpilepsia noted that CBD has anti-seizure properties and a low risk of side effects for people with epilepsy. Studies into CBD effect on neurological disorders suggest that it may help to treat many of the disorders that are linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases.

Could Help Fight Cancer

CBD has been studied for its use as an anti-cancer agent. Areview posted to theBritish Journal of Clinical Pharmacology notes that CBD appears to block cancer cells from spreading around the body and invading an area entirely. The review indicates that this compound tends to suppress the growth of cancer cells and promote the death of these cells. Researchers note that CBD may help in cancer treatment because of its low toxicity levels. They call for it to be studied along with standard treatments, to check for synergistic effects.


Anxiety Disorders

Patients with chronic anxiety are often advised to avoid cannabis, as THC can trigger or amplify anxiety and paranoia in some people. However, a review from Neurotherapeutics suggests that CBD may help to reduce the anxiety felt by people with certain anxiety disorders.

The researchers point to studies showing that CBD may reduce anxiety behaviors in disorders such as:p
 general anxiety disorder
 panic disorder
 social anxiety disorder
 post traumatic stress disorder
 obsessive-compulsive diesorder

The review notes that current medications for these disorders can lead to additional symptoms and side effects and that people may stop taking the drugs because of these unwanted effects. CBD has not shown any adverse effects in these cases to date, and the researchers call for CBD to be studied as a potential treatment method.

Legality

Cannabis, which has high levels of THC is legal for either medicinal or recreational use in some but not all states. CBD derived from the hemp plant, which contained .3% THC or lower is considered Laws may differ between federal and state level, and current marijuana and CBD legislation in the United States can be confusing, even in states where marijuana is legal.

There is an ever-changing number of states that do not necessarily consider marijuana to be legal but have laws directly related to CBD oil. This information is up to date as of July 24, 2017, but the laws frequently change.

The laws vary, but they generally approve CBD oil as legal for treating a range of epileptic conditions at various concentrations. A full list of states that have CBD-specific laws is available here.

Different states also require different levels of prescription to possess and use CBD oil. In Missouri, for example, a person must show that three other treatment options have been unsuccessful in treating epilepsy. If you are considering CBD oil as a treatment for a suitable condition, talk to your local healthcare provider. They will have an understanding of safe CBD sources and local laws surrounding usage.

Research the laws for your own state.

Side effects

Many small-scale studies have looked into the safety of CBD in adults and found that it is well tolerated across a wide range of doses.

There have been no significant side effects in the central nervous system or effects on vital signs and mood among people who use it either slightly or heavily. The most common side effect noted is tiredness. Some people have noticed diarrhea and changes in appetite or weight.

Risks

There are still very little long-term safety data available, and, to date, tests have not been carried out on children. As with any new or alternative treatment option, a patient should discuss CBD with a qualified healthcare practitioner before use. The United States Food and Drug Administration (FDA) has not approved CBD for the treatment of any condition. It can be difficult to know whether a product contains a safe or effective level of CBD or whether the product has the properties and contents stated on its packaging and marketing, so do your research and only purchase CBD from a reputable source who can provide third party verification of the sourcing of the product and the ingredients.

How To Use CBD

CBD oil is used in different ways to relieve the symptoms of different conditions. Some CBD oil products can be mixed into different foods or drinks, taken from a pipette or dropper, or are available as a thick paste to be massaged into the skin. CBD can also be purchased in capsule form.

Other products are provided as sprays that are meant to be administered under the tongue. Edibles such as gummies , lozenges, gum and even CBD infused coffee and tea are becoming increasingly popular methods to delivery.

Here are a few recommended dosages, although these may vary between individuals based on other factors, such as body weight, the concentration of the product, and the condition being treated.

Due to the lack of FDA regulation for CBD products, seek advice from a medical professional before settling on any particular dosage.

All dosages relate to taking CBD orally, including oil, tincture or capsules.

 Chronic pain: Take between 2.5 and 20 milligrams (mg) by mouth for no more than 25 days.
 Epilepsy: Consume between 200 and 300 mg of CBD by mouth daily for up to 4.5 months.
 Movement problems associated with Huntington's disease: Taking 10 mg every day for six weeks can
help ease movements.
 Sleep disorders: Take between 40 and 160 mg.
 Schizophrenia: Consume between 40 and 1,280 mg CBD by mouth daily for up to 4 weeks.
 Glaucoma: One dose of between 20 and 40 mg applied under the tongue can help to relieve pressure in the eye.

However, caution is advised – doses greater than 40 mg might actually increase pressure. As regulation in the U.S. increases, more exact doses and prescriptions will start to emerge.

*Always consult a physician before starting any CBD regimen. All recommendations are subjective and you should start with the lowest dose and see how your body responds and adjust dosages as needed.